The Research Technologist 2 conducts experimental research lab work and/or assists in design of one or more specific phase(s) of entire project(s). This position may complete mathematical calculations, and/or computer tasks and/or assist in judging validity of data. This role follows appropriate protocols, policies, procedures, regulations, Good Clinical and Good Laboratory Practices.
The lab of Dr. Kyle Eagen at Northwestern University focuses on elucidating the molecular and cellular principles underlying DNA folding within eukaryotic cells and how DNA misfolding relates to human disease, including cancer. Northwestern is one of the top ranked universities in the country, and the Feinberg School of Medicine is well known for its exceptional and innovative research and clinical achievements. The Department of Biochemistry and Molecular Genetics has been provided substantial resources by the School of Medicine towards expanding interdisciplinary research in the biochemical, structural, enzymological, molecular, and genetic bases of human disease, with the additional advantage of using multiple model systems in the process. Dr. Eagen’s lab is dedicated to state-of-the-art molecular research using interdisciplinary approaches, the newest of technologies, and the education and training of the next generation of scientists and physician scientists. The lab is located at the downtown Chicago campus in the vibrant Streeterville neighborhood along the shores of Lake Michigan.
The research technician will help initiate a dynamic research program dedicated to understanding the molecular basis of nuclear organization and genome architecture. S/he will be responsible for taking on highly interdisciplinary projects and key functions in this endeavor, including projects focusing on molecular biology, biochemistry, cell biology, as well as genomics approaches using next-generation sequencing technology. S/he will work side-by-side with Dr. Eagen to develop cutting-edge scientific skills as the lab expands into new research areas.
The ideal candidate should be highly motivated, well organized, manage time effectively, and have the ability to work independently as well as part of a team. S/he will also be required to conduct experimental research lab work and assist in the design of one or more specific phases of entire projects. Previous experience with molecular biology and/or biochemistry is essential for this position.
- Following protocols, designs, sets-up and conducts basic experiments.
- Analyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes, validity and/or accuracy.
- Using a fully functioning level of skill, completes the following activities:
- Molecular Biology:
- DNA, RNA, Protein isolation, purification and expression PCR, RT-PCR
- Plasmid preparation
- Cloning, mapping and sequencing of DNA
- Cellular Biology:
- Cell culture, cell isolation
- Functional studies
- Maintains detailed records of results which may include collecting, extracting and entering data.
- Manipulates, interprets and/or presents results.
- Prepares charts and graphs for presentations and publications.
- Performs scientific literature searches in support of research.
- Completes portions of grant applications, manuscripts and publications.
- Tracks and summarizes lab supply expenses.
- Verifies accuracy of invoices.
- Orders and/or maintains inventory of reagent, mice and/or lab supplies.
- Performs other related duties as assigned.
- Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience.
- Demonstrated laboratory experience;
- Demonstrated ability to follow detailed instructions as required by research protocols;
- Demonstrated computer skills, including spreadsheets and basic computations;
- Attention to detail and accurate record keeping;
- Ability to multitask, work and learn independently, and be self-motivated.
- Manual dexterity.
- Successful completion of a bachelor’s, or higher degree in Chemistry or Biology.
- Outstanding interpersonal and communication skills and the ability to work independently and in a team environment.
- A record of taking initiative to solve problems and working to high-quality standards.
As per Northwestern University policy, this position requires a criminal background check. Successful applicants will need to submit to a criminal background check prior to employment.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.