The Freedman Laboratory (http://freedmanlab.com/) is seeking a highly qualified full-time postdoctoral senior fellow to initiate a project using human pluripotent stem cells to develop new, organoid-based microphysiological models of kidney disease and regeneration, under the supervision of Assistant Professor Benjamin Freedman within the Kidney Research Institute, Division of Nephrology, and Institute for Stem Cell and Regenerative Medicine. The applicant will combine stem cell culture and differentiation with bioengineering and microfluidics to build next-generation microphysiological models of human kidney nephrons. This will ultimately lead to better understanding of human disease and new regenerative therapies.This position requires a Ph.D. in cell biology, bioengineering, biophysics, or a related discipline. Experience with human pluripotent stem cells, genome engineering, high-throughput screening, bioinformatics, or microfluidics is a plus. The successful applicant will have demonstrated a high degree of enthusiasm, professionalism, experimental acumen, organizational skills, teamwork, and a thirst for knowledge and scientific progress.This is a 12-month, full-time position with the title of Senior Fellow. The scientist will design and evaluate experiments, actively contribute to the group through innovation and collaboration, present and publish research findings, and participate in Departmental and extramural scholarly activities. The ideal candidate will have a record of creativity and scientific excellence as evidenced by publication record in peer-reviewed journals, a high level of motivation and scientific curiosity along with excellent communication, collaboration, and technical skills. This is a dynamic research environment at the cutting edge of modern medicine and life sciences, with ample opportunities to grow, connect, and learn. The anticipated start is in September 2017.
Experimental duties include: Bioengineering differentiation of human pluripotent stem cells into mini-kidney organoids Microfluidics incorporation of kidney cells into kidney-on-a-chip microphysiological devices Microscopy immunofluorescence, confocal, wide-field, live cell, epithelial cell biology Genome editing guide RNA construction, transfection, screening Therapeutics testing determination of drug clearance and efficacy for candidate drugs
Lab duties:Contributing to laboratory organization and maintenance. Assisting in the training of junior scientists. Presentations of data in lab meetings and publications. Documentation daily record of work performed in files and laboratory notebook.
All University of Washington faculty engage in teaching, research and service.
To apply, please send your CV and cover letter to Dr. Freedman at email@example.com.
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
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